Metabolomics for the discovery of neonatal sepsis biomarkers

Early diagnosis of sepsis is of ultimate importance for patient’s outcome, especially during the neonatal period. The topic has attracted the interest of the scientific community and certain several sepsis biomarkers have been proposed including metabolites mainly involved in energy metabolism. The current project will take a hypothesis free approach performing holistic analysis of small molecule metabolites. Non-targeted analysis with the highest separation power information-rich technologies (NMR, LC-MS, GC-MS) will compare the metabolic profiles of blood and urine of neonates receiving neonatal intensive care at the “Hippokrateion” Hospital of Thessaloniki. Advanced statistical analysis will aim at revealing and validating possible novel biomarker of neonatal sepsis. The project brings together the bioanalytical team of AUTH (with a recognised experience in metabolomics) and the team of clinicians working at the Neonatal intensive care unit, in which are annually treated around 550-600 critically ill preterm and term neonates.


We use cookies to enhance your online experience, offer customized content according to your preferences, improve website’s performance and analyse the traffic.
By selecting “Accept all” you consent to the use of all cookies.
Cookies are small text files which are stored on your device when you visit our website. For further information on cookies, please read the website’s Terms of Use.
Categories of Cookies
These cookies are absolutely necessary for the proper and secure operation of the website and they do not store information which identifies you. Therefore, they cannot be disabled and your consent for their use is not needed, in accordance with the current legislation.
These cookies collect information on how you use the website in order to improve your experience when visiting our website and collect statistical data, such as the website's traffic, the pages the users visit more often etc, by using Google Analytics tools.
These cookies are set and can only be read by the authorized provider of the website in order to personalize the content according to your preferences.
Targeting cookies store information regarding your personal interests and preferences. This type of cookies is not used to display advertisements or any other targeted commercial feature. Third parties may combine information you have provided to them or being collected by you on prior use of their services, for example when navigating to website’s pages embedded videos from our official channel in Youtube.
By selecting “Accept all” you consent to the use of all cookies.