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EDUCATION & SKILLS ›
Genetic association study of the NLRP3 inflammasome-induced pathway with Myasthenia in the Hellenic population
Genetic association study of the NLRP3 inflammasome-induced pathway with Myasthenia in the Hellenic population
YEAR
2015
PROGRAMME
Scientific Projects ›
PROGRAMME
Department of Molecular Biology and Genetics, Democritus University of Thrace

Myasthenia gravis is a complex autoimmune disease, characterized by the production of autoantibodies mainly against the acetylcholine receptor of the neuromuscular junction. Chronic inflammation, which is observed in many tissue-specific autoimmune disorders, could represent a basic field of research in Myasthenia too. Autoinflammatory diseases are characterized by excessive secretion of proinflammatory cytokines, like IL-1β. The production of mature IL-1β is dependent on the action of a protein complex called “NLRP3 inflammasome”, whose role is the cellular response to various pathogenic and non-pathogenic stimuli. Many studies address the existence of genetic association between autoimmune diseases and variations in genes encoding protein components of NLRP3 inflammasome. However, no such study has been ever conducted in the context of Myasthenia. The proposed project aims to identify novel genetic markers that might explain part of the genetic susceptibility of the development of Myasthenia in the Hellenic population, by utilizing research approaches from the field of population genetics.

This project was evaluated and funded as part of the Foundation’s effort to support research teams with all their members being under 40 years old.

GRANTS

EDUCATION & SKILLS
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Postgraduate Scholarships Programme | Academic Year 2024-2025

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“Skills Clubs | Youth Skills for the 21st Century” | School Year 2024-2025

British Council Greece

«Company Junior» and «V-Company» Programmes | School Year 2023-2024

Junior Achievement Greece

“Future Leaders Series” Programme | 2024

ALBA Graduate Business School

Educational Visits to the “Ocean Lab” Educational Space | School Year 2023-2024

Safe Water Sports

Support of Educational Programmes & Screenings

The Goulandris Museum of Natural History

“Eco-Schools” Programme

Hellenic Society for the Protection of Nature 

“Tech Talent School for Educators” Programme | School Year 2023-2024

Social Impact and Innovation (Socialinnov) NPO

“Innovative Classrooms” Teachers Training Programme | School Year 2023-2024

“THE INVENTORS” ROBOTICS AND INNOVATION ACADEMY OF VARI – VOULA – VOULIAGMENI

Training Programme for Educators “Teaching for the Future” | 2024

Training Programme for Secondary Education Teachers | 2024

CERN & Society Foundation

 “CONNECTIONS II” training programme for school psychologists and social workers

“Empowering Vocational Education Students” Programme | School Year 2023-2024

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Hellenic Federation of Enterprises (SEV)

“Educational Routes” Vocational Training and Employability Programme

ODYSSEA

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Regeneration

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Musical Performances & Educational Activities | 2024

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