Science

Programme "Scientific projects"

Measurement and significance of texture and elasticity indices of ultrasound images of subclinical carotid atherosclerosis towards novel markers of cardiovascular risk

Faculty of Medicine, National and Kapodistrian University of Athens (EKPA)

2013

Subclinical atherosclerotic lesions (plaques) of the carotid artery are directly related to the occurrence of stroke, which makes valid identification of vulnerable plaques a crucial public health issue. The often inadequate effectiveness of current diagnostic procedures imposes the search for new diagnostic tools which will enhance validity in risk stratification. The team suggests the investigation of parameters derived from processing and analysis of ultrasound image data of the arterial wall. To this end, texture and motion/elasticity indices will be measured in subclinical atherosclerotic lesions and healthy parts of the wall adjacent to the plaques. The extracted information will be correlated with biochemical markers involved in the destabilization of plaques and the induction of stroke. The study is expected to elucidate the mechanical phenomena that occur in the region of the atherosclerotic carotid artery and reveal novel markers of cardiovascular risk in the context of individualized, non invasive and affordable diagnosis.

Final Report (in Greek)

Coordinator:

Spyretta Golemati, Lecturer in Biomedicine Technology, Faculty of Medicine, National and Kapodistrian University of Athens (EKPA)

Project's Team:

Nikolaos Tsiaparas, PhD Candidate, Faculty of Medicine, National and Kapodistrian University of Athens (EKPA)

Amalia Yianni, Lab Staff, Department of Science of Nutrition-Dietetics, Harokopio University

Symeon Lehareas, PhD Candidate, Faculty of Medicine, National and Kapodistrian University of Athens (EKPA) / Medical resident in Radiodiagnosis at Athens General Hospital "G. Gennimatas"

Emilia Gastounioti, School of Electrical and Computer Engineering, National Technical University of Athens

75, Mikras Assias St.

11527 Goudi

Tel.: +30 210 74 62 002 - 3

Fax: +30 210 74 62 050

www.school.med.uoa.gr

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